


Limited information is available about antibody dynamics after CoronaVac vaccine and the recent supplementing with the BNT162b2 booster. In Brazil, the third dose has been administered, preferably, with the BNT162b2 vaccine (Pfizer-BioNTech, ) ( 3, 4). A decay of circulating SARS-CoV-2 antibodies over time in persons who received CoronaVac (Sinovac, ) have been reported, suggesting the necessity of a third shot of vaccine ( 2). If you are accustomed to Prism 8, you’ll find it easy to switch to Prism 9.Long-term protection against SARS-CoV-2 requires the persistence of vaccine antibodies above protective thresholds, the maintenance of immune memory cells capable of reactivation after subsequent viral exposure, or both ( 1). You’ll just see more options in many places. If you have large data tables, you’ll also notice that Prism runs more quickly.

New analyses : Principal Component Analysis (PCA) and Principal Component Regression (PCR).More automation : Automatically add multiple comparison results to graphs ("Stars on Graph").New Graphs : Bubble plots and other multiple variables graphs from multiple variables data tables.New Graphs : Estimation plots automatically generated from t tests.New Graphs : Actual vs Predicted plot from nonlinear regression.Expanded analyses : New options for Multiple t test analyses (paired, nonparametric, and more).

Expanded analyses : Interpolation from Multiple Linear Regression.More data : Increased data table limits.More data : Text variables and variable types (continuous, categorical, label) for multiple variables data tables.A data table can now have 1024 data sets and 512 sub-columns (up from 512 and 256).No longer runs on 32-bit Windows, as 64-bit Windows has been standard for a decade.You can now enter text variables into multiple variable tables.Each variable (column) is now identified as a continuous (numeric), categorical, or label variable.Multiple and logistic regression can now fit models where one or more of the predictor (independent) variables is entered as text and designated as a categorical variable.Prism knows how to fit models where a categorical variable has three or more levels (possible values).
